PUBLICATIONS
RESEARCH ARTICLES
*Co-first author
- Bieluszewska A, Wulfridge P, Fang KC, Hong Y, Sawada T, Erwin J, Song H, Ming GL, Sarma K. Transcriptomic Analysis Uncovers an Unfolded Protein Response in ADNP Syndrome. Molecular and Cellular Biology (2025). PubMed
- Grothusen GP, Chang R, Cao Z, Zhou N, Mittal M, Datta A, Wulfridge P, Beer T, Wang B, Zhen N, Tang HY, Sarma K, Greenberg RA, Shi J, Busino L. DCAF15 control of cohesin dynamics sustains acute myeloid leukemia. Nature Communications (2024). PubMed
- Wulfridge P*, Davidovich A*, Salvador AC*, Manno GC, Tryggvadottir R, Idrizi A, Huda MN, Bennett BJ, Adams LG, Hansen KD, Threadgill DW, Feinberg AP. Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation. PLoS Genetics (2023). PubMed
- Wulfridge P, Yan Q, Rell N, Doherty J, Jacobson S, Offley S, Deliard S, Feng K, Phillips-Cremins JE, Gardini A, Sarma K. G-quadruplexes associated with R-loops promote CTCF binding. Molecular Cell (2023). PubMed
- Bieluszewska A, Wulfridge P, Doherty J, Ren W, Sarma K. ATRX histone binding and helicase activities have distinct roles in neuronal differentiation. Nucleic Acids Research (2022). PubMed
- Yan Q*, Wulfridge P*, Doherty J, Fernandez-Luna JL, Real PJ, Tang HY, Sarma K. Proximity labeling identifies a repertoire of site-specific R-loop modulators. Nature Communications (2022). PubMed
- Wulfridge P, Sarma K. A nuclease- and bisulfite-based strategy captures strand-specific R-loops genome-wide. eLife (2021). PubMed
- Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K. Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function. Nature Communications (2020). PubMed
- Wulfridge P, Langmead B, Feinberg AP, Hansen KD. Analyzing whole genome bisulfite sequencing data from highly divergent genotypes. Nucleic Acids Research (2019). PubMed
- Barrington WT, Wulfridge P, Wells AE, Rojas CM., Howe SYF, Perry A, Hua K, Pellizzon MA, Hansen KD, Voy BH, Bennett BJ, Pomp D, Feinberg AP, Threadgill DW. Improving Metabolic Health Through Precision Dietetics in Mice. Genetics (2018). PubMed
- Fang F, Zuo Q, Pilrose J, Wang Y, Shen C, Li M, Wulfridge P, Matei D, Nephew KP. Decitabine reactivated pathways in platinum resistant ovarian cancer. Oncotarget (2014). PubMed
REVIEWS/METHODS ARTICLES
- Mudiyanselage SDD*, Wulfridge P*, Sarma K. The paradox of R-loops: guardians of the genome or drivers of disease? Genome Research (2025). PubMed
- Wulfridge P, Sarma K. Intertwining roles of R-loops and G-quadruplexes in DNA repair, transcription and genome organization. Nature Cell Biology (2024). PubMed
- Wulfridge P, Yan Q, Sarma K. Targeted nuclease approaches for mapping native R-loops. Methods in Molecular Biology (2022). PubMed